¿Son equivalentes los diferentes métodos para estimar la función renal en los adultos mayores?

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dc.contributor.authorVega, Jorge
dc.contributor.authorHuidobro E., Juan Pablo
dc.contributor.authorSepúlveda, Rodrigo Andrés
dc.date.accessioned2022-11-30T02:46:26Z
dc.date.available2022-11-30T02:46:26Z
dc.date.issued2021
dc.description.abstractBackground: Glomerular filtration rate (GFR) estimation in older adults using a creatinine clearance/24-hour (CrCl) or an equation based on serum creatinine, are often considered equivalent by clinicians. Aim: To compare GFR estimated (eGFR) with the available equations and measured CrCl in patients ≥ 70 years. A secondary aim was to know the differences in chronic kidney disease (CKD) classification, when using the different eGFR formulas. Patients and Methods: In 144 patients aged 77 ± 5 years (58% men), CrCl was measured and GFR was estimated using MDRD, CKD-EPI, BIS-1 and FAS formulas. The eGFR and the stage of CKD were compared according to the different equations used. Results: GFR estimated by MDRD and CKD-EPI equations was 7.8 and 8.4 mL/min/1.73 m2 lower than 24-hour ClCr, respectively. This difference was even greater using the BIS-1 and FAS equations. Twenty-four-hour CrCl classified 47.2% of the patients in a category of renal function > 60 mL/min/1.73 m2 while MDRD and CKD-EPI equations classified just over a third, and BIS-1 and FAS formulas around 20% of the patients. Conclusions: The practice of considering equivalent the GFR estimation using the creatinine-based equations with measured creatinine clearance in older adults should be reconsidered, because their results differ markedly.en_ES
dc.facultadFacultad de Medicinaen_ES
dc.file.nameHuidobro_son2021.pdf
dc.identifier.citationVega Jorge, Huidobro E. Juan Pablo, Sepúlveda Rodrigo Andrés. ¿Son equivalentes los diferentes métodos para estimar la función renal en los adultos mayores?. Rev. méd. Chile [Internet]. 2021 Feb [citado 2022 Nov 21] ; 149( 2 ): 187-195. Disponible en: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872021000200187&lng=es. http://dx.doi.org/10.4067/s0034-98872021000200187.en_ES
dc.identifier.doihttp://dx.doi.org/10.4067/s0034-98872021000200187
dc.identifier.urihttp://repositoriobibliotecas.uv.cl/handle/uvscl/7374
dc.languagees
dc.publisherSociedad Médica De Santiago
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.sourceRevista médica de Chile
dc.subjectCREATININEen_ES
dc.subjectGLOMERULAR FILTRATION RATEen_ES
dc.subjectKIDNEY FUNCTION TESTSen_ES
dc.subjectRENAL INSUFFICIENCY, CHRONICen_ES
dc.title¿Son equivalentes los diferentes métodos para estimar la función renal en los adultos mayores?
dc.typeArticulo
uv.departamentoDepartamento de Medicina

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