Hypofractionated radiation therapy for early breast cancer: Follow up of a new treatment standard

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dc.contributor.authorSolis Campos, Jose Antonio
dc.contributor.authorVeillon Contreras, Gabriel Antonio
dc.contributor.authorTudela, Benjamin Tobias
dc.date.accessioned2022-03-08T19:20:01Z
dc.date.available2022-03-08T19:20:01Z
dc.date.issued2020-08-25
dc.description.abstractAim: To assess the oncological outcomes of patients with early breast cancer treated with breastconserving surgery and adjuvant hypofractionated radiation therapy. Methods and Material: This retrospective analysis included all patients ≥50 year of age with T1-2 N0 M0 breast cancer treated at our Radiation Oncology Unit between 2008 and 2011. Whole-breast radiation therapy was delivered to a dose of 42.5 Gy in 16 fractions, without boost. The primary outcome was local control. Results: 212 patients were identified. With a median follow up of 60 months, we found 3% local recurrence and 5.3% regional and/or distant recurrences. At the moment of data analysis, 17 patients had died. Out of 5 local recurrences, 2 had previously had a distant recurrence, both of them died. The other three were still alive at the last follow up. These results are comparable to those observed in Phase III trials that use this fractionation scheme. Conclusions: The results obtained with this retrospective analysis are comparable to those obtained in large randomized trials. This data also supports the use of hypofractionated radiation therapy in Latin America. Hypofractionated radiation therapy for early breast cancer patients should be the standard adjuvant treatment.en_ES
dc.facultadFacultad de Medicinaen_ES
dc.identifier.doihttps://doi.org/10.1016/j.rpor.2020.08.013
dc.identifier.urihttp://repositoriobibliotecas.uv.cl/handle/uvscl/3793
dc.language.isoenen_ES
dc.publisherElsevieren_ES
dc.rights© 2020 Greater Poland Cancer Centre. Published by Elsevier B.V. All rights reserved.en_ES
dc.sourceReports of Practical Oncology and Radiotherapyen_ES
dc.subjectEARLY BREAST CANCERen_ES
dc.subjectHYPOFRATIONATED WHOLE BREAST RADIATIONen_ES
dc.subjectTHERAPYen_ES
dc.titleHypofractionated radiation therapy for early breast cancer: Follow up of a new treatment standarden_ES
dc.typeArticuloen_ES
uv.catalogadorRCR DIBRAen_ES
uv.departamentoDepartamento de Oncologiaen_ES

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