Orcokinin neuropeptides regulate reproduction in the fruit fly, Drosophila melanogaster

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dc.contributor.authorSilva, Valeria
dc.contributor.authorPalacios-Muñoz, Angelina
dc.contributor.authorVolonté, Mariano
dc.contributor.authorFrenkel, Lía
dc.contributor.authorEwer, John
dc.contributor.authorOns, Sheila
dc.date.accessioned2022-11-30T02:46:59Z
dc.date.available2022-11-30T02:46:59Z
dc.date.issued2021
dc.description.abstractIn animals, neuropeptidergic signaling is essential for the regulation of survival and reproduction. In insects, Orcokinins are poorly studied, despite their high level of conservation among different orders. In particular, there are currently no reports on the role of Orcokinins in the experimental insect model, the fruit fly, Drosophila melanogaster. In the present work, we made use of the genetic tools available in this species to investigate the role of Orcokinins in the regulation of different innate behaviors including ecdysis, sleep, locomotor activity, oviposition, and courtship. We found that RNAi-mediated knockdown of the orcokinin gene caused a disinhibition of male courtship behavior, including the occurrence of male to male courtship, which is rarely seen in wildtype flies. In addition, orcokinin gene silencing caused a reduction in egg production. Orcokinin is emerging as an important neuropeptide family in the regulation of the physiology of insects from different orders. In the case of the fruit fly, our results suggest an important role in reproductive success.en_ES
dc.facultadFacultad de Cienciasen_ES
dc.file.nameSilva_Orc2021.pdf
dc.identifier.doihttps://doi.org/10.1016/j.ibmb.2021.103676
dc.identifier.urihttp://repositoriobibliotecas.uv.cl/handle/uvscl/7544
dc.languageen
dc.publisherElsevier
dc.sourceInsect Biochemistry and Molecular Biology
dc.subjectINNATE BEHAVIORSen_ES
dc.subjectECDYSISen_ES
dc.subjectSLEEPen_ES
dc.subjectLOCOMOTOR ACTIVITYen_ES
dc.subjectCOURTSHIPen_ES
dc.subjectOVIPOSITIONen_ES
dc.titleOrcokinin neuropeptides regulate reproduction in the fruit fly, Drosophila melanogaster
dc.typeArticulo
uv.departamentoCentro Interdisciplinario de Neurociencia de Valparaiso

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